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American Society of Microbiology ABMM Sample Questions:
1. Which of the following organisms is an obligate intracellular bacterium transmitted by arthropod vectors and is a common cause of Rocky Mountain Spotted Fever?
A) Coxiella burnetii
B) Chlamydia trachomatis
C) Borrelia burgdorferi
D) Rickettsia rickettsii
2. In a clinical microbiology laboratory, quality control testing of Mueller-Hinton agar used for disk diffusion susceptibility testing involves checking the zone sizes for E. coli ATCC 25922, S. aureus ATCC 25923, and
P. aeruginosa ATCC 27853. What is the primary purpose of including P. aeruginosa ATCC 27853 in this QC?
A) To confirm the correct pH of the agar medium
B) To ensure appropriate concentration of calcium and magnesium ions affecting aminoglycoside activity
C) To assess the performance of agents primarily active against Gram-positive organisms
D) To verify the performance of cell wall active agents like penicillin
3. A patient develops a severe diarrheal illness after returning from a backpacking trip where they drank untreated stream water. Stool examination reveals motile trophozoites with multiple flagella and a prominent ventral sucking disk. The MOST likely causative agent is:
A) Cyclospora cayetanensis
B) Cryptosporidium parvum
C) Giardia lamblia
D) Entamoeba histolytica
4. A clinical microbiology laboratory is investigating an outbreak of vancomycin-resistantEnterococcus faecium (VRE) in a hospital. Whole-genome sequencing of isolates from different patients reveals the presence of the vanA operon on a mobile genetic element that is highly conserved across all isolates. This finding MOST strongly suggests:
A) Clonal spread of a single VRE strain carrying the vanA operon.
B) Independent acquisition of vancomycin resistance by different E. faecium strains.
C) Selection of vancomycin-resistant mutants within a susceptible E. faecium population due to antibiotic pressure.
D) Horizontal transfer of the vanA operon to multiple susceptible E. faecium strains.
5. An outbreak of gastroenteritis occurs among attendees of a company picnic. Epidemiological investigation points towards contaminated potato salad. Stool cultures from affected individuals grow non-lactose fermenting, Gram-negative rods that are H2S positive on TSI agar. Which pathogen is most likely responsible?
A) Enterotoxigenic E. coli (ETEC)
B) Salmonella Enteritidis
C) Vibrio cholerae
D) Shigella sonnei
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: B | Question # 3 Answer: C | Question # 4 Answer: A | Question # 5 Answer: B |






